Tfrc rab11
Web18 Nov 2024 · The molecular links between tissue-level morphogenesis and the differentiation of cell lineages in the pancreas remain elusive despite a decade of studies. … Web30 Sep 2024 · Confocal microscopy colocalized REP15 and RAB15 to the perinuclear region of HeLa cells. Sucrose gradient cell fractionation and organelle-specific …
Tfrc rab11
Did you know?
Web1 Mar 2007 · Polarized trafficking of MT1-MMP is triggered by beta1 integrin-mediated adhesion to collagen, and is required for protease localization at invasive structures. Localization of MT1-MMP within VSV-G/Rab8-positive vesicles, but not in Rab11/Tf/TfRc-positive compartment in invasive cells, suggests the involvement of the exocytic traffic …
WebTransferrin receptor 1. Transferrin receptor protein 1 ( TfR1 ), also known as C luster of D ifferentiation 71 ( CD71 ), is a protein that in humans is encoded by the TFRC gene. [5] [6] … Web8 Sep 2024 · Grab also interacts with Tfrc and Rab11. Activated Rab8 is postulated to bind to the Sec15 subunit of the exocyst complex and thus recruits the exocyst complex to the …
Web4 Jan 2024 · Many disorders block and subvert basic cellular processes in order to boost their progression. One protein family that is prone to be altered in human cancers is the small GTPase RAB11 family, the master regulator of vesicular trafficking. RAB11 isoforms function as membrane organizers connecting the transport of cargoes towards the … WebRab11 shifted to the membrane fraction in RhoB-KD HSB-2 cells (fig. S6, D and E). RhoB and Rab11 appeared to affect the distribution of both LFA-1 and each other within the HSB-2 …
Web6 May 2016 · Rab11 regulates, through the interaction with its effector Rab11-FIP3 (Horgan & McCaffrey, 2009), the subcellular localization of the GTPase Rac1 in resting T cells, and …
Web23 Jan 2007 · Rab11b, which shares 90% sequence identity with Rab11a, displayed similar Evi5 binding characteristics as Rab11a, with a dissociation constant of 50 nM. As a control for binding specificity, Evi5 was shown to be unable to bind GMP-PNP-loaded versions of Rab1 and Rab3b, as well as ARF6, another GTPase implicated in vesicular trafficking ( 28 ). easy clean humidifiers for homeWeb26 May 1998 · Rab11 is a small GTP-binding protein that in cultured mammalian cells has been shown to be concentrated in the pericentriolar endosomal recycling compartment and to play a key role in passage of the recycling transferrin receptor through that compartment [Ullrich, O., Reinsch, S., Urbé, S., Zerial, M. & Parton, R. G. (1996) J. Cell Biol. 135, … cup phone holder for thick phone caseWebRAB11 family interacting protein 4 (class II) P value c FDR, false discovery rate A4gnt alpha-1,4-N-acetylglucosaminyltransferase Enzymes Acacb acetyl-Coenzyme A carboxylase … easy cleaning coopWeb8 Sep 2024 · The Tfrc mRNA level was unchanged in Grab knockout cells (supplemental Figure 4C-D), indicating that the reduced Tfrc protein abundance was not attributed to its decreased expression. To discern whether Grab deficiency caused a specific defect in Tfrc trafficking or a more general defect in endocytic recycling, we examined the localization … cup phone holder sand spikeWebOur catalog antibodies can be used in popular research areas including epigenetics, DNA damage/repair, cancer, and immunology. Whichever research area you are interested in, our p cup phone holder hand sanitizerWebFinally, we describe a GRAB deletion mutant (GRAB Δ223–228) that is deficient in Rab11-binding ability. These data identify GRAB as a dual Rab-binding protein that could … easy clean hingesMembers of the Rab11 subfamily act in recycling of proteins from the endosomes to the plasma membrane, in transport of molecules from the trans-Golgi network to the plasma membrane and in phagocytosis. This subfamily also acts in polarized transport in epithelial cells. Whereas most studies refer to the Rab11a isoform, little is known about Rab11b so far. Rab11b localizes predominantly in the pericentriolar recycling compartment and serves as an important compone… easycleaning-filter