2024 Gstm1 breast cancer

Gstm1 breast cancer

Author: kafy

August undefined, 2024

WebThe articles evaluating the correlations between response to chemotherapy and GSTP1, GSTT1, and GSTM1 polymorphisms in breast cancer patients were comprehensively reviewed. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated to measure the strength of the associations. WebMar 27, 2024 · Since oral cancer is a global health concern and alcohol and tobacco consumption are major risk factors involved in its carcinogenesis, the aim of this study was to evaluate the Fagerström and AUDIT tests as likely screening tools for oral cancer and their correlation with the expression of CYP1A1, GSTM1, GSTP1, and GSTT1 genes …

Combined effects of GSTM1 and GSTT1 polymorphisms on breast ... - L…

WebMar 27, 2024 · Since oral cancer is a global health concern and alcohol and tobacco consumption are major risk factors involved in its carcinogenesis, the aim of this study … WebSensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study. he4992

Горовенко Наталія Григорівна — Вікіпедія

WebTable 3. Association of GST gene polymorphism with breast cancer development. Discussion. The current study is the first to report association between breast cancer and GSTT1 and GSTM1 genes polymorphism in Ghanaian patients. The motivation for this study was to determine the association between GST polymorphic genes (GSTM1 and … WebPolymorphisms in the glutathione transferase enzymes (GSTs) genes have been associated with susceptibility to develop breast cancer (BC), but few are known regarding its role on this disease prognosis and impact on antioxidant status. This study evaluated the polymorphisms of GSTM1 and GSTT1 genes a … WebAug 1, 2024 · A multiplex qualitative real-time PCR method was used to detect the presence or absence of the GSTM1 and GSTT1 gene in the genomic DNA samples of the participants. Results: The frequencies of the GSTM1 and GSTT1 null genotypes in 198 breast cancer patients were 65.70% and 33.30%, respectively. The overall survival at 1, … he4969

Gstm1 breast cancer

Effects of GSTT1 and GSTM1 polymorphisms in glutathione levels …

WebSeveral investigations of Hodgkin's lymphoma, ovarian cancer, colorectal cancer, and breast cancer have found improved survival rates associated with polymorphic forms of GSTT1, GSTM1, and GSTP1 ... WebFeb 10, 2024 · Moreover, high expression of GSTP1 confers resistance of breast cancer cells to adriamycin by promoting autophagy . In addition, ... Vutuc C and Micksche M: Polymorphisms of glutathione-S-transferase genes (GSTP1, GSTM1 and GSTT1) and prostate-cancer risk. Int J Cancer. 95:152–155. 2001. View Article: Google Scholar: …

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WebJul 30, 2015 · Introduction. Breast cancer is the most frequently diagnosed type of cancer [], and the risk of recurrence is influenced by the stage at initial presentation and the underlying biology of the tumor.Despite the known prognostic factors for breast cancer, including tumor size, nodal involvement, grade, lymphovascular invasion, and the … WebThe 10 SNP loci were polymorphic of different frequency in the breast cancer patients. The combinations with GSTP1 genotypes and GSTMI genotypes were related to anthracycline-based chemotherapy efficacy （P = 0.037）, and the low GSTs activity group （GSTP1 variant allele ＋ GSTM1 null） showed the best effects （85.7%）.

WebUsing log-transformed whole blood arsenic concentrations as the dependent variable in a General Linear Model, there was a significant interaction between GSTP1 and autism spectrum disorder case status, but not for GSTT1 and GSTM1. In breast cancer cells, GSTP1 inhibits the expression of RIP140, a negative regulator of estrogen receptor alpha ... WebIn the current study, we investigated the relationship between the levels of aromatic DNA adducts in breast tissues and polymorphisms of the drug-metabolizing genes cytochrome P4501A1 (CYP1A1), N-acetyltransferase-2 (NAT2), and glutathione S-transferase M1 (GSTM1), in 166 women having breast cancer.

WebApr 15, 2009 · Abstract. Signal peptide-CUB-epidermal growth factor–like domain-containing protein 2 (SCUBE2), originally identified from the endothelium and several nonendothelial primary cell types, was recently shown to be expressed in invasive breast carcinomas. However, the protein localization and biological significance of SCUBE2 in breast …

WebNov 1, 2001 · Abstract. The glutathione S-transferase (GST) genes are involved in the metabolism of various carcinogens. Deletion polymorphisms in the GSTM1 and GSTT1 …

WebNational Center for Biotechnology Information he4a0 nm-d291WebApr 28, 2005 · Application of the new GSTM1 assay to a breast cancer case-control study revealed that the relative risk of breast cancer for the +/+ genotype compared to the -/- genotype was 2.83 (95% confidence interval 1.45-5.59; P=0.002), suggesting a protective effect of the GSTM1 deletion [Cancer Res. 64 (2004) 1233-1236]. gold fall ash treeWebIn this study 14.28% of cases had at least one family history of cancer, among them 5.72 represented breast cancer, 1.43% represented familial breast cancer plus other types … gold falling off a wheelchairWebGSTM1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. gold falcon custom jewelersWebSep 20, 2024 · The gel electrophoresis technique was used to detect the genotype for the GSTM1, GSTT1, and GSTP1 genetic variants. GSTM1 genotyping was based on the … he4aWebJun 11, 2010 · GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer Genet Mol Res . 2010 Jun 11;9(2):1045-53. doi: 10.4238/vol9-2gmr726. he 4 alabWeb// Jie Ma 1, * , Shao-Liang Zhu 2, * , Yang Liu 3, * , Xiang-Yang Huang 1 and Dan-Ke Su 1 1 Department of Radiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China 2 Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China 3 Department of Radiotherapy, Affiliated Tumor Hospital of … he4alo