Cyclodextrin rotaxanes and polyrotaxanes
WebDec 30, 2024 · Niemann-Pick Type C is a rare metabolic disorder characterized by the cellular accumulation of cholesterol within endosomal and lysosomal compartments. 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) containing polyrotaxanes represent an attractive approach for treating this disease due to their ability to circulate in the blood stream for … WebMar 1, 2024 · Les cyclodextrines, qui constituent un macrocycle de choix pour la formation de rotaxanes et polyrotaxanes, ont fait l'objet de plusieurs revues majeures par Wenz …
Cyclodextrin rotaxanes and polyrotaxanes
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WebSep 21, 1999 · Solvent-free synthesis of pseudopolyrotaxane and polyrotaxane: Efficient threading complexation of a cyclodextrin wheel and a linear polymer axle to yield pseudopolyrotaxane and its fixation to polyrotaxane by the direct grinding of a solid mixture.
WebApr 11, 2024 · The present article deals with the structural characteristics and synthetic methods of rotaxanes, polyrotaxanes, and polyrotaxane networks having cyclodextrin and crown ether as the wheel ... Web机译：含有冠醚的乙烯基轮烷交联剂，用于亲水和硬旋转旋转式网络聚合物. 5. Dendrimeric and polymeric rotaxanes incorporating the Loeb recognition motif. [D] . Tramontozzi, David A. 2005. 机译：结合了Loeb识别基序的树枝状和聚合物轮烷。. 6. Rotaxane-Based Mechanophores Enable Polymers ...
WebAug 10, 2005 · Cyclodextrin Rotaxanes and Polyrotaxanes. Chemical Reviews 2006, 106 (3) , 782-817. DOI: 10.1021/cr970027+. Masaya Naito, Takaaki Fujino, Shinya Tajima, Shinobu Miyagawa, Kazuyuki Yoshida, Hajime Inoue, Hiroaki Takagawa, Tsuneomi Kawasaki, Yuji Tokunaga. Ring size affects the kinetic and thermodynamic formation of … WebJan 19, 2024 · Ratcheting is essential to devise motors. For molecular motors, information ratchets have been developed and proved efficient. These ratchets basically modify the energetic landscape of the system depending on information= that until now has been the relative position of the motor components. Here, we show that by using a cone-shaped …
WebMar 9, 2024 · Acid-degradable PRXs composed of α-cyclodextrin (α-CD) as a cyclic molecule, poly(ethylene glycol) (PEG) as a polymer axis, and … Doxorubicin (DOX)-conjugated acid-degradable polyrotaxanes (PRXs) were designed as supramolecular drug carriers capable of releasing drugs in acidic cellular environments.
WebThis discovery – which is made coincidentally at around the same time by Daryle Busch in Kansas – leads to a blossoming of research on catenanes and rotaxanes (also … psw hiring in peterboroughWebJul 1, 2008 · Cyclodextrin rotaxanes and polyrotaxanes Rotaxane is a kind of molecular species consisting of linear components (so-called axis) threaded into cyclic components (so-called rings), where the dissociation of the ring from the axis is hindered by bulky groups (so-called stoppers) at both ends of the axis ( Wenz et al., 2006 ). psw home careWebOct 5, 2024 · Consequently, CD-based host–guest complexes are often employed as templates for the synthesis of mechanically bonded molecules (mechanomolecules) such as catenanes, rotaxanes, and polyrotaxanes in particular. hort cash loansWebIn this article, we review the design, synthesis and characterization of rotaxanes and polyrotaxanes of cyclodextrins threaded by an alkyl chain or a poly (ethylene glycol) as … psw highschoolWebJan 1, 2014 · Polyrotaxanes in which numerous α-CD molecules are threaded on a PEG chain have been prepared by mixing α-CD and PEG bis-amines with 2,4-dinitrofluorobenzene, which is sufficiently bulky to prevent α-CD from dethreading (Fig. 3) [2, 5, 6].This is the first example of a polyrotaxane, named as a “molecular necklace.” α-CD … hort carolineWebApr 7, 2024 · Rotaxanes, and their pseudorotaxane and polyrotaxane relatives, serve as prototypes for molecular-level switches and machines and as components in materials like elastic polymers and 3D printing inks. The rigidity and flexibility of these molecules is a characteristic feature of their design. hort christoph arnold schuleWebCyclodextrin-Based Rotaxanes: from Rotaxanes to Polyrotaxanes and Further to Functional Materials. European Journal of Organic Chemistry 2024, 2024 (21) , 3344 … psw home theater