Atf6a kda
WebThe ATF6α luminal domain contains two cysteine residues (C467 and C618) that either form an intrachain disulfide (C467-618) in the monomer or interchain disulfide bonded dimers (C467-467 or C618-618) ( 16) ( Fig. 1 A ). WebFeb 15, 2016 · ATF6a, Chondrocyte hypertrophy, UPR, Transcription factor, Regulation INTRODUCTION In eukaryotic cells, endoplasmic reticulum (ER) stress is known to initiate a signaling pathway called the unfolded protein response (UPR) ( Hetz, 2012; Zhang and Kaufman, 2004; Ron and Walter, 2007 ).
Atf6a kda
Did you know?
WebMar 21, 2024 · GeneCards Summary for ATF6 Gene. ATF6 (Activating Transcription Factor 6) is a Protein Coding gene. Diseases associated with ATF6 include Achromatopsia 7 … HMOX1 (Heme Oxygenase 1) is a Protein Coding gene. Diseases associated with … XBP1 (X-Box Binding Protein 1) is a Protein Coding gene. Diseases associated with … SERPINE1 (Serpin Family E Member 1) is a Protein Coding gene. Diseases … FCGR3A (Fc Gamma Receptor IIIa) is a Protein Coding gene. Diseases … EPCAM (Epithelial Cell Adhesion Molecule) is a Protein Coding gene. Diseases … MPZ (Myelin Protein Zero) is a Protein Coding gene. Diseases associated with … SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator … HEXA (Hexosaminidase Subunit Alpha) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … EGR1 (Early Growth Response 1) is a Protein Coding gene. Diseases … http://www.immunoway.com/CHome/Pdf/?id=2055
WebJun 1, 2015 · ATF6 is a member of the ATF/CREB (cAMP response element–binding protein) family of basic leucine-zipper (bZIP) transcription factors encoded by two paralogs, ATF6 and ATF6B. ATF6A is a key... WebThe basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE. During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis.
WebATF6, ATF6 alpha, ATF6A Observed MW 50 kDa,100 kDa. Application. Tested Application ELISA, WB Recommended dilution WB: 1:200-1:2000. Uniprot information. UniProt ID P18850. Images. Image 4. MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab10404(ATF6 Antibody) at dilution of 1:1000. WebActivation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake Sarah E. Kobylewski1 & Kimberly A. Henderson1 & Kristin E. Yamada1 & Curtis D. Eckhert1,2 Received: 19 July 2016/Accepted: 15 August 2016
WebDec 10, 2016 · The 29 kDa CHOP is a member of the C/EBP family of transcription factors. CHOP was upregulated in VZV-infected monolayers incubated for 48 h, in concert with the appearance of the spliced form of XBP1 . The parallel results for XBP1 and CHOP suggested that ER stress conditions became extreme as most of the cells became infected.
WebAntibodies (Ab) against BIP (78 kDa), ATF6 (90 kDa), glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and horseradish peroxidase (HRP)-conjugated goat anti-rabbit secondary Ab were purchased from Proteintech, Wuhan, China. Phosphorylated PERK (p-PERK; Thr 981, 125 kDa) Ab was purchased from Santa Cruz Biotechnology, Santa … top rated fantasy draft picks 2016WebATF6 is originally a 90 kDa type II transmembrane glycoprotein that is converted to a 50 kDa soluble nuclear form, retaining its N-terminal domain, including the leucine zipper. … top rated fantasy football defenses 2015WebATF6 is a key transcriptional activator of the unfolded protein response (UPR), which allows mammalian cells to maintain cellular homeostasis when they are subjected to environmental and physiological stresses that target the ER (reviewed in Shen, 2005 & Prywes, 2005). top rated fantasy defenses nfl 2021Webunfolded protein response, activated by oasis family transcription factors, promotes astrocyte differentiation top rated fantasy football draft kitsWeb75 kDa. ( Note) Product Note This antibody was raised against the C-terminus of human ATF6 alpha, meaning it can only detect the uncleaved form. ... ATF6A Cellular … top rated family size air fryerWebThe Bureau and Law Enforcement. ATF recognizes the role that firearms play in violent crimes and pursues an integrated regulatory and enforcement strategy. Investigative … top rated fantasy football defenses 2022WebMay 25, 2024 · Indeed, ATF6α is a potent transcriptional activator whereas ATF6β, a poor transcriptional activator, may inhibit activation by ATF6α [ 7 ]. In contrast with the protein kinases PERK and IRE1 (type I transmembrane proteins), ATF6α is a 90 kDa type II transmembrane glycoprotein and member of the bZIP transcription factor family [ 8 ]. top rated fantasy movies imdb